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Theoretical and Practical Approach for Transdermal Drug Delivery using Microneedle for Successful Skin Penetration

Jeevan J.Mahakud[1], Ziaur Reheman[2]
[1]Department of electronics and Communication engineering, Institute of technical education and research, Bhubaneswar, Odisha, India
[2]Department of electronics and instrumentation engineering, Institute of technical education and research, Bhubaneswar, Odisha, India

With the advent of MEMS, transdermal drug delivery has been developed to increase skin permeability for drug transport. Various microneedle structures have been analyzed theoretically as well as through simulation using COMSOL Multiphysics®. Then computational fluid dynamics has been presented in order to study the behavior of the fluid flow inside the microneedle cavity. In this report, the ...

Modeling of Fluid Flow and Heat Transfer During a Steam-Thermolysis Process for Recycling Carbon Fiber Reinforced Polymer

A. Oliveira Nunes[1], Y. Soudais[1], R. Barna[1], A. Bounacer[1], Y. Yang[1]
[1]Centre RAPSODEE - Ecole des Mines d'Albi, Albi, France

Different types of technologies to recycle carbon fiber reinforced polymer (CFRP) waste have been studied, for example: pyrolysis, solvolysis and steam-thermolysis. The steam-thermolysis is a process that combines pyrolysis and superheated steam at atmospheric pressure to decompose the organic matrix of the composite. The waste is introduced into a bench-scale reactor heated at high temperatures ...

Modeling Voltammetry of a Rotating Disk Electrode

A. Giaccherini [1], A. Lavacchi [2],
[1] INSTM, Firenze, Italy
[2] ICCOM - CNR, Firenze, Italy

In this work we report a numerical model of a Rotating Disk Electrode (RDE) voltammetry in a finite size domain. Thus, explaining the discrepancy of the diffusion coefficient obtained from the experimental rotating speed, with respect to the literature data. We achieved a very good agreement at the limiting current and at the unexpected peak for the RDE voltammetry at 2000 rpm and different ...

Model Development and Implementation of a Membrane Shift Reactor

J. Völler[1], M. Follmann[1], C. Bayer[1], and T. Melin[1]

[1]AVT Chemical Process Engineering, RWTH Aachen University, Aachen, Germany

Low temperature fuel cells require hydrogen of high purity for electricity production to avoid catalyst poisoning. To purify hydrogenrich flue gases from hydrocarbon steam reforming membrane shift reactors with a metal membranes may be utilized. A model of a tubular membrane shift reactor with a hydrogenseparating palladium membrane is modeled in the COMSOL Multiphysics® Chemical Engineering ...

Optimization of Jet Mixer Geometry and Mixing Studies - new

A. Egedy[1], B. Molnar[1], T. Varga[1], T. Chován[1]
[1]Department of Process Engineering, University of Pannonia, Veszprém, Hungary

The primary aim of using jet as mixer, like in case of other mixing devices, is to increase the heat and mass transfer between the phases. Beside the injection position the geometry of the jet mixer and the injection nozzle has a major effect on the injection. In our study COMSOL Multiphysics software was used to carry out the experimental and simulation of the different jet geometries. The jet ...

Geometric Multigrid Solver and Experimental Validation in Laser Surface Remelting

M. M. Pariona [1], F. de Oliveira [1],
[1] State University of Ponta Grossa, PR, Brazil

INTRODUCTION The purpose of this work is to verify the effect of Multigrid method on the CPU time for the resolution of the heat transfer model, based on the Finite Element Method (FEM), in order to simulate the laser surface remelting (LSR) of the Al–1.5 wt.% Fe alloy. To accelerate the convergence of Single grid methods, Multigrid method (MG) was employed in order to reduce the CPU time. In ...

Direct Numerical Simulation of Time Evolution of Vortex Ring

M. Hashiguchi [1],
[1] Keisoku Engineering System Co., Ltd., Chiyoda-ku, Tokyo, Japan

Vortex ring can be useful to generate thrust force for e.g., jellyfish, but its mechanism has not been clarified. In this field, it seems that numerical simulation has an important role of understanding the propulsion mechanism of creature. A vortex ring in a tube, refered to confined vortex ring, have been far less studied compared with unconfined vortex rings, despite their importance for many ...

Transport Phenomena and Shrinkage Modeling During Convective Drying of Vegetables

S. Curcio[1] and M. Aversa[1]
[1]Department of Engineering Modeling, University of Calabria, Arcavacata di Rende, CS, Italy

The aim of the present work is the formulation of a theoretical model describing the transport phenomena involved in food drying process. The attention has been focused on the simultaneous transfer of momentum, heat and mass occurring in a convective drier where hot dry air flows, in turbulent conditions, around the food sample. The proposed model does not rely on the specification of ...

Solving a Two-Scale Model for Vacuum Drying by Using COMSOL Multiphysics

S. Sandoval Torres[1]
[1]Instituto Politécnico Nacional, CIIDIR, Oaxaca, Mexico

Drying of porous materials is characterized by the invasion of a gaseous phase replacing the evaporating liquid phase. Vacuum drying is an advanced method applied to oakwood to diminish discoloration, so understand its physics is a very important task. In this work, a two-scale model is solved to simulate vacuum drying of oakwood. A two scale model describes the physics of wood-water relations ...

Modelling and Simulation of Single Phase Fluid Flow and Heat Transfer in Packed Beds using COMSOL Multiphysics

S. Sachdev[1], S. Pareek[1], B. Mahadevan[1], A. Deshpande[1]
[1]Department of Chemical Engineering, BITS Pilani Goa Campus, Zuarinagar, Goa, India

Computational fluid dynamics has emerged as an advanced tool for studying detailed behavior of fluid flow and heat transfer characteristics in many chemical engineering applications like packed beds. Packed beds play an important role in various chemical industries. Hence understanding the fluid flow behavior and temperature variation in different sections of packed bed is essential. Geometric ...